protein domain

Prediction of Protein Domain Folding Classes

蛋白质结构域折叠类型的离散量理论预测

RESULTS : We present a semi-automatic procedure for deriving a novel hierarchical classification of protein domain structures ( CATH ) .

结果：我们提出了一个半自动的程序用于获得蛋白质域结构的一个新的层次分类（CATH）。

Protein domain is a particular protein structure with independent functions .

蛋白质的结构域是蛋白质中具有特异结构和独立功能的区域。

Immunogenicity and antigenicity of Japanese encephalitis virus envelope protein domain ⅲ

日本脑炎病毒SA14-14-2E蛋白结构域Ⅲ的抗原性和免疫原性分析

Analyze the rare codons in the encoding sequence of DENV ⅱ envelope protein domain ⅲ; 3 .

分析编码登革Ⅱ型病毒E蛋白第三结构域序列的稀有密码子：3。

Alternatively , investigators might analyze the three-dimensional structure of a protein domain and then design drugs that bind tightly to that region .

或者，研究人员也可以分析某个蛋白质区间的立体构造，设计出与该区间紧密结合的药物。

Research on Multiple Sequence Alignment is significant for recognition of protein domain structure , prediction of secondary structure , gene identification , and molecular phylogenetic analysis and so on .

研究多序列比对对于蛋白质的功能域识别、二级结构预测、基因识别以及分子系统发育分析等具有重要的意义。

The amino acid sequence , protein domain and motifs , and three-dimension structure of γ D-crystallin protein and its mutant were analyzed and predicted .

因此本研究对γD晶体蛋白及其突变体进行了氨基酸序列分析，结构域预测及立体结构模拟等生物信息学研究，以探讨P23T突变对γD晶体蛋白结构与功能的影响。

Bioinformatic methods were employed to analyze the homology of the nucleotide and amino acids sequence of beta subunit gene and its possible protein domain and transmembrane topology .

并应用生物信息学方法分析该基因的同源性、蛋白结构域及跨膜拓扑结构。

58 amino acids constitute a conserved regions DNA binding protein domain in its middle region , the 14th and 19th amino acids site are valine and glutamic acid , respectively .

中间由58个氨基酸组成的保守的DNA结合蛋白区AP2结构域，其第14位和19位分别为缬氨酸（V）和谷氨酸（E）。

Recent progress in internalization mechanism of protein transduction domain

蛋白转导域内在化机制的研究进展

Reconstruction of an intracellular transduction system based on HIV-1 TAT protein transduction domain

一种基于HIV-1TAT蛋白质转导结构域细胞内转导系统的成功改建

Construction and expression of a vector containing protein transduction domain and bcr / abl fusion gene

蛋白转导结构域-bcr/abl融合基因的构建和表达

Secretion Expression and Characterization of Human Mature Nerve Growth Factor with Protein Transduction Domain of HIV-Tat

带有HIVTAT-蛋白转导域的人成熟神经生长因子的分泌表达及鉴定

Advances in Study on HIV-Tat Protein Transduction Domain

HIV-Tat蛋白转导域的研究进展

Activation effects of BCR / ABL antigen on CML T cells mediated by protein transduction domain

蛋白转导域介导BCR/ABL抗原对CML患者T细胞的活化作用

Protein transduction domain ( PTD ) is a short peptide , which can ferry molecules across the cell membrane .

蛋白转导域（PTDs）是一段富含碱性氨基酸的短肽。

TAT protein transduction domain mediates transmembrane delivery of BCR / ABL fusion protein into tissue cells of mice in vivo

TAT蛋白转导结构域介导的BCR/ABL融合蛋白在小鼠体内的跨膜转运

OBJECTIVE A protein transduction domain ( PTD ) derived from the HIV TAT protein could benefit macromolecules across blood brain barrier ( BBB ) .

目的来源于人类免疫缺陷病毒（HIV）-I型编码的反式激活蛋白（TAT）中的蛋白质转导域（PTD），能介导生物大分子通过血脑屏障。

Modification of Bcl-xl gene with sequence of secretory signal peptide and protein transduction domain may improve the efficiency of endothelial cell antiapoptosis by Bcl-xl gene transfer .

通过分泌信号肽和穿膜肽序列修饰Bcl-xl基因，可能使编码的Bcl-xl蛋白具有分泌和穿膜功能，而增加Bcl-xl基因治疗抗内皮细胞凋亡的效果。

To construct a recombinant plasmid containing protein transduction domain ( PTD ) and brain derived neurotrophic factor ( BDNF ) fusion gene and express in E.

构建含蛋白转导结构域（PTD）与脑源性神经营养因子（BDNF）融合基因的质粒，并在大肠肝菌中表达。

Bioinformatics analysis showed that there was a significant protein signal domain in the deduced amino acid sequence , and a similar 3D structure could be found in the SWiSS-MODEL database .

经过生物信息学分析，发现所推导的氨基酸序列具有明显的CYP蛋白信号域，且可以在SWiSS-MODEL数据库中搜索到与之相近的三维结构。

A novel gene containing an acyl carrier protein like domain encoding region was cloned from human brain cDNA with the method of adapter primer polymerase chain reaction ( PCR ) .

本研究采用锚定引物PCR法从正常人脑cDNA中克隆到一个含有酰基携带蛋白（ACP）样结构域的新基因。

Aim To explore the method of transfering oncoprotein bcr / abl , mediated by protein transduction domain ( PTD ), in order to provide the experimental basis for immune therapy .

目的探讨蛋白转导结构域（PTD）介导的转导bcr/abl癌蛋白片段的方法，为进行免疫治疗提供实验依据。

Recently , it has been found that the protein transduction domain has the ability of permeating cell membrane and can exert bioactivity by taking permeability cell membrane of macromolecular peptides into cells .

近年来，人们发现蛋白转导结构域具有穿透细胞膜的能力，并能携带大分子肽类通透细胞膜进入细胞内发挥生物活性。

Methods : With molecular cloning technique , The recombinant vector termed pTAT-HA-BDNF was constructed , which could encode both TAT protein transduction domain and human brain-derived neurotrophic factor without signal peptide .

方法：采用分子克隆方法构建带有TAT蛋白转导区序列及无信号肽序列人BDNF基因的原核表达载体pTAT-HA-BDNF。

It is believed that the neural networks of this paper can provide a more appropriate protein / domain structural class assignment criterion with a complete classification attribute vector and a bigger and more representative training set built up .

在建立更完备的域结构类特征向量和更有代表性的训练集的基础上，所述方法将为蛋白质域结构分类领域提供新的分类基准。

CDK11 ~ ( p58 ) contains a Ser / Thr protein kinase domain in the middle of the molecule , an N-terminal domain and a C-terminal domain with unknown function .

CDK11~（p58）蛋白则有一个位于中间的丝／苏氨酸激酶活性结构域和功能尚不明确的氨基端、羧基端。

In this area , we predicted that four candidate sequences which are highly relevant to the gene family regulating leaf morphology in Arabidopsis thaliana through highly conservative protein structure domain search , which provides beneficial enlightenment for follow-up study .

通过高度保守的蛋白质结构域搜索，在此区域预测到4条与拟南芥的叶形调控家族基因高度相关的候选序列，为后续研究提供了有益启示。

This study make a more comprehensive analysis from the similarity of amino acid sequence , composition , physicochemical properties , hydrophobicity , hydrophilicity , sequence alignment , phylogenetic tree , protein functional domain , secondary and tertiary structure prediction and other aspects .

并从氨基酸序列的相似性、组成成分、理化性质、疏水性／亲水性、序列比对、进化树、功能域、二级结构和三级结构等方面进行了预测和较为全面的分析。